MolNFT v1 · #142185 · protein
FAD complex of piga
5ZW2 · L-prolyl-[peptidyl-carrier protein] dehydrogenase: “FAD complex of piga”. X-ray diffraction, 3 ligands (O4B, FAD, CL), 3 pockets (best druggability 0.73). MolNFT v1 #142185 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5ZW2
- Type
- protein
- Length
- 383 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-prolyl-[peptidyl-carrier protein] dehydrogenase
- EC
- 1.3.8.14
- UniProt
- Q5W271
- Ligands
- O4B, FAD, CL
- Pockets
- 3 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 57% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-prolyl-[peptidyl-carrier protein] dehydrogenase (EC 1.3.8.14) | protein | 383 | 57% helix, 15% strand | Q5W271 |
Ligands and binding sites
- O4B · 1,4,7,10,13,16-hexaoxacyclooctadecane · ligand · 2 copies · chains A
- FAD · Flavin-adenine dinucleotide · ligand · chains A
- CL · Chloride ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 7 copies · chains A
- ACT · Acetate ion · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 418 | 0.73 | 0.83 | 52 | FAD, ACT |
| 2 | 133 | 0.67 | 0.89 | 26 | EDO |
| 3 | 98 | 0.35 | 0.73 | 16 | EDO |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5W271
- Elsewhere: RCSB PDB 5ZW2 · PDBe 5ZW2 · UniProt Q5W271
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