Crystal structure of human G protein coupled receptor

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• 9JU · N-(adamantan-1-yl)-1-(5-hydroxypentyl)-4-methyl-5-phenyl-1H-pyrazole-3-carboxamide · ligand · chains A
• OLA · Oleic acid · ligand · chains A
• SO4 · Sulfate ion · ion · 5 copies · chains A
• OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 3 copies · chains A
• PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
• EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · 2 copies · chains A
• PG4 · Tetraethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 5ZTY · Crystal structure of human G protein coupled receptor · the same entry in another collection · chain A against A, TM-score 1.00
• P34972 · AlphaFold monomer V2.0 prediction for cannabinoid receptor 2 (P34972) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P34972
• Every structure of UniProt D9IEF7
• Elsewhere: RCSB PDB 5ZTY · PDBe 5ZTY · UniProt P34972 · UniProt D9IEF7