MolNFT v1 · #139376 · protein
Staphylococcus aureus ftsz 12-316 complexed with TXA6101
5XDU · Cell division protein ftsz: “Staphylococcus aureus ftsz 12-316 complexed with TXA6101”. X-ray diffraction, 3 ligands (GDP, ZI6, CA), 3 pockets (best druggability 0.74). MolNFT v1 #139376 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5XDU
- Type
- protein
- Length
- 306 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell division protein ftsz
- UniProt
- Q6GHP9
- Ligands
- GDP, ZI6, CA
- Pockets
- 3 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell division protein ftsz | protein | 306 | 46% helix, 24% strand | Q6GHP9 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains A
- ZI6 · 3-[[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]methoxy]-2,6-bis(fluoranyl)benzamide · ligand · chains A
- CA · Calcium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 221 | 0.74 | 0.89 | 36 | ZI6 |
| 2 | 231 | 0.59 | 0.80 | 38 | GDP |
| 3 | 121 | 0.47 | 0.78 | 16 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6GHP9
- Elsewhere: RCSB PDB 5XDU · PDBe 5XDU · UniProt Q6GHP9
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