MolNFT v1 · #138484 · protein
Crystal structure of the human mitochondrial cysteine desulfurase in complex with ISD11 and iron-sulfur cluster scaffold protein ISCU1, and E. COLI ACP1 protein at 3.15A
5WKP: “Crystal structure of the human mitochondrial cysteine desulfurase in complex with ISD11 and iron-sulfur…”. X-ray diffraction, 2 ligands (PLP, 8Q1). MolNFT v1 #138484 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WKP
- Type
- protein
- Length
- 1,344 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y697, Q9HD34, B7MJ81, Q9H1K1
- Ligands
- PLP, 8Q1
Structure
x-ray diffraction · 8 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 396 | — | Q9Y697 |
| B | — | protein | 81 | — | Q9HD34 |
| C | — | protein | 72 | — | B7MJ81 |
| D | — | protein | 118 | — | Q9H1K1 |
| E | — | protein | 398 | — | Q9Y697 |
| F | — | protein | 82 | — | Q9HD34 |
| G | — | protein | 71 | — | B7MJ81 |
| H | — | protein | 126 | — | Q9H1K1 |
Ligands and binding sites
- PLP · Pyridoxal-5'-phosphate · ligand · 2 copies · chains A, E
- 8Q1 · S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy) butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate · ligand · 2 copies · chains B, C, F, G
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5WKP · Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11… · the same entry in another collection · chain H against H, TM-score 1.00
- Q9Y697 · AlphaFold monomer V2.0 prediction for cysteine desulfurase, mitochondrial (Q9Y697) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q9H1K1 · AlphaFold monomer V2.0 prediction for iron-sulfur cluster assembly enzyme iscu… · a predicted model of the same protein · chain H against A, TM-score 0.99
- Q9HD34 · AlphaFold monomer V2.0 prediction for lyr motif-containing protein 4 (Q9HD34) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y697
- Every structure of UniProt Q9HD34
- Every structure of UniProt B7MJ81
- Every structure of UniProt Q9H1K1
- Elsewhere: RCSB PDB 5WKP · PDBe 5WKP · UniProt Q9Y697 · UniProt Q9HD34 · UniProt B7MJ81 · UniProt Q9H1K1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.