MolNFT v1 · #138331 · protein

Ligand-bound RAS:SOS:RAS complex

5WFQ: “Ligand-bound RAS:SOS:RAS complex”. X-ray diffraction, 3 ligands (GNP, 5UV, MG). MolNFT v1 #138331 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5WFQ
Type: protein
Length: 804 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P01112, Q07889
Ligands: GNP, 5UV, MG

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
Q	—	protein	166	—	P01112
R	—	protein	167	—	P01112
N	—	protein	471	—	Q07889

Ligands and binding sites

GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains Q
5UV · 7-chloranyl-~{N}-(3-chloranyl-4-fluoranyl-phenyl)-1,2, 3,4-tetrahydroacridin-9-amine · ligand · chains N
MG · Magnesium ion · metal · chains Q

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5WFQ · Ligand-bound Ras:SOS:Ras complex · the same entry in another collection · chain Q against Q, TM-score 1.00
Q07889 · AlphaFold monomer V2.0 prediction for son of sevenless homolog 1 (Q07889) · a predicted model of the same protein · chain N against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01112
Every structure of UniProt Q07889
Elsewhere: RCSB PDB 5WFQ · PDBe 5WFQ · UniProt P01112 · UniProt Q07889

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