MolNFT v1 · #137877 · protein
Crystal structure of a 1:1:1 FGF23-FGFR1C-aklotho ternary complex
5W21: “Crystal structure of a 1:1:1 FGF23-FGFR1C-aklotho ternary complex”. X-ray diffraction, 2 ligands (NAG, ZN). MolNFT v1 #137877 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5W21
- Type
- protein
- Length
- 1,317 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9UEF7, Q9GZV9, P11362
- Ligands
- NAG, ZN
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 922 | — | Q9UEF7 |
| B | — | protein | 182 | — | Q9GZV9 |
| C | — | protein | 213 | — | P11362 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 7 copies · chains A
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5W21 · Crystal Structure of a 1:1:1 FGF23-FGFR1c-aKlotho Ternary Complex · the same entry in another collection · chain C against C, TM-score 1.00
- Q9UEF7 · AlphaFold monomer V2.0 prediction for klotho (Q9UEF7) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q9GZV9 · AlphaFold monomer V2.0 prediction for fibroblast growth factor 23 (Q9GZV9) · a predicted model of the same protein · chain B against A, TM-score 0.94
- P11362 · AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 1 (P11362) · a predicted model of the same protein · chain C against A, TM-score 0.58
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UEF7
- Every structure of UniProt Q9GZV9
- Every structure of UniProt P11362
- Elsewhere: RCSB PDB 5W21 · PDBe 5W21 · UniProt Q9UEF7 · UniProt Q9GZV9 · UniProt P11362
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