MolNFT v1 · #135151 · protein
Factor viia in complex with the inhibitor (5R,11R)-11-[(1-amino-4- fluoroisoquinolin-6-YL)AMINO]-16-(cyclopropylsulfonyl)-7-(2,2- difluoroethoxy)-5,13-dimethyl-2,13-DIAZATRICYCLO[13.3.1.1~6, 10~]ICOSA-1(19),6(20),7,9,15,17-hexaene-3,12-dione
5TQG: “Factor viia in complex with the inhibitor (5R,11R)-11-[(1-amino-4…”. X-ray diffraction, 3 ligands (7KS, CA, SO4). MolNFT v1 #135151 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TQG
- Type
- protein
- Length
- 305 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P08709
- Ligands
- 7KS, CA, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H | — | protein | 250 | — | P08709 |
| L | — | protein | 55 | — | P08709 |
Ligands and binding sites
- 7KS · (5R,11R)-11-[(1-amino-4-fluoroisoquinolin-6-yl)amino]-16-(cyclopropylsulfonyl)-7-(2,2-difluoroethoxy)-5,13-dimethyl-2,13-diazatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaene-3,12-dione · ligand · chains H
- CA · Calcium ion · metal · chains H
- SO4 · Sulfate ion · ion · 4 copies · chains H, L
- GOL · Glycerol · additive · 4 copies · chains H, L
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P08709 · AlphaFold monomer V2.0 prediction for coagulation factor VII (P08709) · a predicted model of the same protein · chain H against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08709
- Elsewhere: RCSB PDB 5TQG · PDBe 5TQG · UniProt P08709
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