MolNFT v1 · #127944 · protein

Crystal structure of the ARP4-N-ACTIN(APO-state) heterodimer bound by a nanobody

5NBL: “Crystal structure of the ARP4-N-ACTIN(APO-state) heterodimer bound by a nanobody”. X-ray diffraction, 2 ligands (ATP, CA). MolNFT v1 #127944 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5NBL
Type: protein
Length: 1,810 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P80428, P60010
Ligands: ATP, CA

Structure

x-ray diffraction · 6 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	397	—	P80428
C, D	—	protein	366	—	P60010
E	—	protein	122	—	—
F	—	protein	124	—	—
G	—	protein	18	—	—
H	—	protein	20	—	—

Ligands and binding sites

ATP · Adenosine-5'-triphosphate · ligand · 2 copies · chains A, B
CA · Calcium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5NBL · Crystal structure of the Arp4-N-actin(APO-state) heterodimer bound by a nanobody · the same entry in another collection · chain H against H, TM-score 1.00
P80428 · AlphaFold monomer V2.0 prediction for actin-related protein 4 (P80428) · a predicted model of the same protein · chain A against A, TM-score 0.99
P60010 · AlphaFold monomer V2.0 prediction for actin (P60010) · a predicted model of the same protein · chain C against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P80428
Every structure of UniProt P60010
Elsewhere: RCSB PDB 5NBL · PDBe 5NBL · UniProt P80428 · UniProt P60010

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