UniProt P80428
Actin-related protein 4 (P80428)
Actin-related protein 4 (UniProt P80428): 17 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 71 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P80428
- Protein
- Actin-related protein 4
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 71 · 7 records with a druggable one
Structures
18 records of P80428 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QB0 | Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP | x-ray diffraction | A, B, C, D | — | — |
| 3QB0 | Crystal structure of actin-related protein ARP4 from S. cerevisiae complexed with ATP | x-ray diffraction | A, B, C, D | — | — |
| 5I9E | Crystal structure of a nuclear actin ternary complex | x-ray diffraction | A, C | MG, ATP | 14 (best 0.89) |
| 5I9E | Crystal structure of a nuclear actin ternary complex | x-ray diffraction | A, C | — | — |
| 5NBL | Crystal structure of the Arp4-N-actin(APO-state) heterodimer bound by a nanobody | x-ray diffraction | A, B | CA, ATP | 16 (best 0.88) |
| 5NBL | Crystal structure of the ARP4-N-ACTIN(APO-state) heterodimer bound by a nanobody | x-ray diffraction | A, B | CA, ATP | — |
| 5NBM | Crystal structure of the Arp4-N-actin(ATP-state) heterodimer bound by a nanobody | x-ray diffraction | A, B | CA, ATP | 16 (best 0.88) |
| 5NBM | Crystal structure of the ARP4-N-ACTIN(ATP-state) heterodimer bound by a nanobody | x-ray diffraction | A, B | CA, ATP | — |
| 5NBN | Crystal structure of the Arp4-N-actin-Arp8-Ino80HSA module of INO80 | x-ray diffraction | A, B | CA, ATP | — |
| 5NBN | Crystal structure of the ARP4-N-actin-ARP8-INO80HSA module of INO80 | x-ray diffraction | A, B | CA, ATP | — |
| 5Y81 | NuA4 TEEAA sub-complex | electron microscopy | F | — | 5 (best 0.87) |
| 5Y81 | NUA4 teeaa sub-complex | electron microscopy | F | — | — |
| 7VVY | Tra module of NUA4 | electron microscopy | F | MG, ATP | — |
| 7VVZ | NUA4 bound to the nucleosome | electron microscopy | F | MG, ATP | — |
| 8A5A | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80 | electron microscopy | W | ATP, MG | 8 (best 0.89) |
| 8A5O | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of S. cerevisiae INO80 | electron microscopy | W | AGS, MG | 8 (best 0.88) |
| 8ESC | Structure of the Yeast NuA4 Histone Acetyltransferase Complex | electron microscopy | R | ATP, MG | 4 (best 0.90) |
| P80428 | AlphaFold monomer V2.0 prediction for actin-related protein 4 (P80428) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5NBL chain A against the predicted model P80428: TM-score 0.99, RMSD 0.77 Å
- 5NBL chain A against the predicted model P80428: TM-score 0.99, RMSD 0.77 Å
- 5NBL chain B against the predicted model P80428: TM-score 0.99, RMSD 0.77 Å
- 5NBL chain B against the predicted model P80428: TM-score 0.99, RMSD 0.77 Å
- 5NBM chain B against the predicted model P80428: TM-score 0.99, RMSD 0.88 Å
- 5NBM chain B against the predicted model P80428: TM-score 0.99, RMSD 0.88 Å
- 5NBM chain A against the predicted model P80428: TM-score 0.99, RMSD 0.88 Å
- 5NBM chain A against the predicted model P80428: TM-score 0.99, RMSD 0.88 Å
- 5NBN chain B against the predicted model P80428: TM-score 0.99, RMSD 0.90 Å
- 5NBN chain B against the predicted model P80428: TM-score 0.99, RMSD 0.90 Å
Elsewhere
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