GL1X · GenesisL1 explorer

MolNFT v1 · #114928 · protein

Crystal structure of gtb + udp-glc + H-antigen acceptor

5C4E · Histo-blood group abo system transferase: “Crystal structure of gtb + udp-glc + H-antigen acceptor”. X-ray diffraction, 3 ligands (UDP, 4YA, MN), 1 pocket (best druggability 0.77). MolNFT v1 #114928 on GenesisL1: 3D structure…

PDB
5C4E
Type
protein
Length
290 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Histo-blood group abo system transferase
EC
2.4.1.40, 2.4.1.37
UniProt
P16442
Ligands
UDP, 4YA, MN
Pockets
1 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHisto-blood group abo system transferase (EC 2.4.1.40, 2.4.1.37)protein29033% helix, 19% strandP16442

Ligands and binding sites

  • UDP · Uridine-5'-diphosphate · ligand · chains A
  • 4YA · hexyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside · ligand · chains A
  • MN · Manganese (II) ion · metal · chains A
  • PG0 · 2-(2-methoxyethoxy)ethanol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15430.770.8446MN, UDP, 4YA

Compared structures

  • 5C4E · Crystal structure of GTB + UDP-Glc + H-antigen acceptor · the same entry in another collection · chain A against A, TM-score 1.00
  • P16442 · AlphaFold monomer V2.0 prediction for histo-blood group abo system transferase (P16442) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.