GL1X · GenesisL1 explorer

MolNFT v1 · #540628 · protein

AlphaFold monomer V2.0 prediction for zwei ig domain protein zig-8 (G5ED00)

G5ED00: “AlphaFold monomer V2.0 prediction for zwei ig domain protein zig-8 (G5ED00)”. 5 pockets (best druggability 0.58). MolNFT v1 #540628 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
G5ED00
Type
protein
Length
268 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
Molecule
Zwei ig domain protein zig-8
UniProt
G5ED00
Pockets
5 · best druggability 0.58

Structure

1 distinct chain · 9% helix, 40% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AZwei ig domain protein zig-8protein2689% helix, 40% strandG5ED00

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13590.580.7643empty
2740.420.8022empty
3500.340.7911empty
4700.320.7515empty
5620.290.7415empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 6PLL · Crystal structure of the zig-8 IG1 homodimer · an experimental structure of the same protein · chain A against A, TM-score 0.44
  • 6PLL · Crystal structure of the ZIG-8 IG1 homodimer · an experimental structure of the same protein · chain A against A, TM-score 0.44
  • 6ON9 · Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, tetragonal form · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 6ON9 · Crystal structure of the zig-8-rig-5 IG1-IG1 heterodimer, tetragonal form · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 6ONB · Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, monoclinic form · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 6ONB · Crystal structure of the zig-8-rig-5 IG1-IG1 heterodimer, monoclinic form · an experimental structure of the same protein · chain A against A, TM-score 0.43

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