MolNFT v1 · #494989 · protein
AlphaFold monomer V2.0 prediction for tubulinyl-tyr carboxypeptidase 2 (Q86V25)
Q86V25: “AlphaFold monomer V2.0 prediction for tubulinyl-tyr carboxypeptidase 2 (Q86V25)”. 3 pockets (best druggability 0.74). MolNFT v1 #494989 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q86V25
- Type
- protein
- Length
- 355 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBFcDC1D91370Eb31E0B1B0ff22a8664FCf743544
- Molecule
- Tubulinyl-tyr carboxypeptidase 2
- UniProt
- Q86V25
- Pockets
- 3 · best druggability 0.74
Structure
1 distinct chain · 29% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tubulinyl-tyr carboxypeptidase 2 | protein | 355 | 29% helix, 14% strand | Q86V25 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 767 | 0.74 | 0.79 | 72 | empty |
| 2 | 211 | 0.49 | 0.75 | 27 | empty |
| 3 | 82 | 0.43 | 0.79 | 18 | empty |
Compared structures
- 6J4S · Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and… · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 6J4S · Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and… · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 6J4Q · Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and… · an experimental structure of the same protein · chain A against A, TM-score 0.69
- 6J4V · Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and… · an experimental structure of the same protein · chain A against A, TM-score 0.69
- 6QBY · Crystal structure of vash 2 in complex with svbp · an experimental structure of the same protein · chain A against C, TM-score 0.69
- 6J4P · Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and… · an experimental structure of the same protein · chain A against A, TM-score 0.69
- 6J4O · Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and… · an experimental structure of the same protein · chain A against A, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q86V25
- Elsewhere: UniProt Q86V25 · AlphaFold DB Q86V25
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