UniProt Q86V25
Tubulinyl-Tyr carboxypeptidase 2 (Q86V25)
Tubulinyl-Tyr carboxypeptidase 2 (UniProt Q86V25), EC 3.4.17.17: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q86V25
- Protein
- Tubulinyl-Tyr carboxypeptidase 2
- EC
- 3.4.17.17
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 21 · 3 records with a druggable one
Structures
9 records of Q86V25 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6J4O | Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional… | x-ray diffraction | A | PO4 | — |
| 6J4P | Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional… | x-ray diffraction | A | BJL | — |
| 6J4Q | Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional… | x-ray diffraction | A, C, F, J | TQ8 | 15 (best 0.78) |
| 6J4Q | Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional… | x-ray diffraction | A, C, F, J | TQ8 | — |
| 6J4S | Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional… | x-ray diffraction | A | PO4 | 3 (best 0.59) |
| 6J4S | Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional… | x-ray diffraction | A | PO4 | — |
| 6J4V | Structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional… | x-ray diffraction | A | PO4 | — |
| 6QBY | Crystal structure of vash 2 in complex with svbp | x-ray diffraction | A, C | — | — |
| Q86V25 | AlphaFold monomer V2.0 prediction for tubulinyl-tyr carboxypeptidase 2 (Q86V25) | predicted | A | — | 3 (best 0.74) |
Ligands
Experiment against prediction
- 6J4S chain A against the predicted model Q86V25: TM-score 0.99, RMSD 0.42 Å
- 6J4S chain A against the predicted model Q86V25: TM-score 0.99, RMSD 0.42 Å
- 6QBY chain C against the predicted model Q86V25: TM-score 0.99, RMSD 0.44 Å
- 6J4Q chain A against the predicted model Q86V25: TM-score 0.99, RMSD 0.46 Å
- 6J4Q chain A against the predicted model Q86V25: TM-score 0.99, RMSD 0.46 Å
- 6QBY chain A against the predicted model Q86V25: TM-score 0.99, RMSD 0.47 Å
- 6J4Q chain C against the predicted model Q86V25: TM-score 0.99, RMSD 0.54 Å
- 6J4Q chain C against the predicted model Q86V25: TM-score 0.99, RMSD 0.54 Å
- 6J4V chain A against the predicted model Q86V25: TM-score 0.99, RMSD 0.72 Å
- 6J4Q chain F against the predicted model Q86V25: TM-score 0.99, RMSD 0.64 Å
Elsewhere
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