MolNFT v1 · #487035 · protein
AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 25 (Q9UHP3)
Q9UHP3: “AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 25 (Q9UHP3)”. 12 pockets (best druggability 0.75). MolNFT v1 #487035 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UHP3
- Type
- protein
- Length
- 1,055 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
- Molecule
- Ubiquitin carboxyl-terminal hydrolase 25
- UniProt
- Q9UHP3
- Pockets
- 12 · best druggability 0.75
Structure
1 distinct chain · 51% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin carboxyl-terminal hydrolase 25 | protein | 1055 | 51% helix, 10% strand | Q9UHP3 |
Pockets
12 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 914 | 0.75 | 0.78 | 94 | empty |
| 2 | 329 | 0.72 | 0.85 | 39 | empty |
| 3 | 51 | 0.70 | 0.98 | 14 | empty |
| 4 | 742 | 0.67 | 0.75 | 58 | empty |
| 5 | 351 | 0.60 | 0.77 | 37 | empty |
Compared structures
- 6H4J · Usp25 catalytic domain · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 6H4J · USP25 catalytic domain · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 5O71 · Crystal structure of human USP25 · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 5O71 · Crystal structure of human USP25 · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 6HEL · Structure of human USP25 · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 6HEL · Structure of human USP25 · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 6HEM · Structure of the C-terminal domain of USP25 (748-1048) · an experimental structure of the same protein · chain A against A, TM-score 0.28
- 6HEM · Structure of the C-terminal domain of USP25 (748-1048) · an experimental structure of the same protein · chain A against A, TM-score 0.28
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UHP3
- Elsewhere: UniProt Q9UHP3 · AlphaFold DB Q9UHP3
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