MolNFT v1 · #467821 · protein
AlphaFold monomer V2.0 prediction for ENDOSOMAL/LYSOSOMAL potassium channel TMEM175 (Q9BSA9)
Q9BSA9: “AlphaFold monomer V2.0 prediction for ENDOSOMAL/LYSOSOMAL potassium channel TMEM175 (Q9BSA9)”. 5 pockets (best druggability 0.81). MolNFT v1 #467821 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9BSA9
- Type
- protein
- Length
- 504 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xccC4FB4F7e27ce58a8B5D4D5a0B27999b032ba3c
- Molecule
- ENDOSOMAL/LYSOSOMAL potassium channel TMEM175
- UniProt
- Q9BSA9
- Pockets
- 5 · best druggability 0.81
Structure
1 distinct chain · 72% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ENDOSOMAL/LYSOSOMAL potassium channel TMEM175 | protein | 504 | 72% helix, 1% strand | Q9BSA9 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 387 | 0.81 | 0.89 | 55 | empty |
| 2 | 442 | 0.60 | 0.76 | 36 | empty |
| 3 | 114 | 0.51 | 0.82 | 21 | empty |
| 4 | 71 | 0.38 | 0.77 | 18 | empty |
| 5 | 62 | 0.28 | 0.73 | 13 | empty |
Compared structures
- 6W8P · Structure of membrane protein with ions · an experimental structure of the same protein · chain A against B, TM-score 0.75
- 6W8P · Structure of membrane protein with ions · an experimental structure of the same protein · chain A against B, TM-score 0.75
- 6W8O · Structure of an apo membrane protein · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 6W8O · Structure of an Apo membrane protein · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 7LF6 · Structure of lysosomal membrane protein · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 7LF6 · Structure of lysosomal membrane protein · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 6W8N · Structure of a trans-membrane protein · an experimental structure of the same protein · chain A against B, TM-score 0.72
- 6W8N · Structure of a trans-membrane protein · an experimental structure of the same protein · chain A against A, TM-score 0.72
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BSA9
- Elsewhere: UniProt Q9BSA9 · AlphaFold DB Q9BSA9
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