MolNFT v1 · #465107 · protein

AlphaFold monomer V2.0 prediction for tho complex subunit THP2 (O13539)

O13539: “AlphaFold monomer V2.0 prediction for tho complex subunit THP2 (O13539)”. 2 pockets (best druggability 0.44). MolNFT v1 #465107 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O13539
Type: protein
Length: 261 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
Molecule: Tho complex subunit THP2
UniProt: O13539
Pockets: 2 · best druggability 0.44

Structure

1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tho complex subunit THP2	protein	261	76% helix, 0% strand	O13539

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	152	0.44	0.75	24	empty
2	87	0.32	0.73	19	empty

Compared structures

7APX · Yeast tho-SUB2 complex · an experimental structure of the same protein · chain A against C, TM-score 0.33
7APX · yeast THO-Sub2 complex · an experimental structure of the same protein · chain A against C, TM-score 0.33
7V2W · Protomer structure from the dimer of yeast tho complex · an experimental structure of the same protein · chain A against J, TM-score 0.33
7V2Y · Cryo-EM structure of yeast tho complex with SUB2 · an experimental structure of the same protein · chain A against E, TM-score 0.30
7LUV · Cryo-EM structure of the yeast tho-SUB2 complex · an experimental structure of the same protein · chain A against B, TM-score 0.29

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O13539
Elsewhere: UniProt O13539 · AlphaFold DB O13539

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