MolNFT v1 · #459999 · protein
AlphaFold monomer V2.0 prediction for activated RNA polymerase II transcriptional coactivator P15 (P53999)
P53999: “AlphaFold monomer V2.0 prediction for activated RNA polymerase II transcriptional coactivator P15 (P53999)”. 1 pocket (best druggability 0.27). MolNFT v1 #459999 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P53999
- Type
- protein
- Length
- 127 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x92C13525f7d099F9849aB1EF45113915218e2BB0
- Molecule
- Activated RNA polymerase II transcriptional coactivator P15
- UniProt
- P53999
- Pockets
- 1 · best druggability 0.27
Structure
1 distinct chain · 15% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Activated RNA polymerase II transcriptional coactivator P15 | protein | 127 | 15% helix, 27% strand | P53999 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.27 | 0.73 | 14 | empty |
Compared structures
- 4USG · Crystal structure of PC4 W89Y mutant complex with DNA · an experimental structure of the same protein · chain A against A, TM-score 0.51
- 4USG · Crystal structure of PC4 W89Y mutant complex with DNA · an experimental structure of the same protein · chain A against A, TM-score 0.51
- 1PCF · Human transcriptional coactivator PC4 C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.51
- 1PCF · Human transcriptional coactivator PC4 C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.51
- 7E4W · Human Transcriptional Co-activator PC4 (C-terminal Domain) in space group P1211 · an experimental structure of the same protein · chain A against A, TM-score 0.51
- 7E4W · Human transcriptional co-activator PC4 (C-terminal domain) in space group P1211 · an experimental structure of the same protein · chain A against A, TM-score 0.51
- 2C62 · Crystal structure of the human transcription cofactor PC4 in complex with single-stranded… · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 2C62 · Crystal Structure of the Human Transcription Cofactor PC4 in Complex with Single-Stranded… · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 2PHE · Model for VP16 binding to PC4 · an experimental structure of the same protein · chain A against A, TM-score 0.47
- 2PHE · Model for VP16 binding to PC4 · an experimental structure of the same protein · chain A against A, TM-score 0.47
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53999
- Elsewhere: UniProt P53999 · AlphaFold DB P53999
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