UniProt P53999
Activated RNA polymerase II transcriptional coactivator P15 (P53999)
Activated RNA polymerase II transcriptional coactivator P15 (UniProt P53999): 10 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P53999
- Protein
- Activated RNA polymerase II transcriptional coactivator P15
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
11 records of P53999 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PCF | Human transcriptional coactivator PC4 C-terminal domain | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1PCF | Human transcriptional coactivator PC4 C-terminal domain | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2C62 | Crystal Structure of the Human Transcription Cofactor PC4 in Complex with Single-Stranded DNA | x-ray diffraction | A, B | — | — |
| 2C62 | Crystal structure of the human transcription cofactor PC4 in complex with single-stranded DNA | x-ray diffraction | A, B | — | — |
| 2PHE | Model for VP16 binding to PC4 | solution nmr | A, B | — | — |
| 2PHE | Model for VP16 binding to PC4 | solution nmr | A, B | — | — |
| 4USG | Crystal structure of PC4 W89Y mutant complex with DNA | x-ray diffraction | A, B | — | — |
| 4USG | Crystal structure of PC4 W89Y mutant complex with DNA | x-ray diffraction | A, B | — | — |
| 7E4W | Human Transcriptional Co-activator PC4 (C-terminal Domain) in space group P1211 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 7E4W | Human transcriptional co-activator PC4 (C-terminal domain) in space group P1211 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| P53999 | AlphaFold monomer V2.0 prediction for activated RNA polymerase II transcriptional coactivator P15… | predicted | A | — | 1 (best 0.27) |
Experiment against prediction
- 4USG chain A against the predicted model P53999: TM-score 0.96, RMSD 0.63 Å
- 4USG chain A against the predicted model P53999: TM-score 0.96, RMSD 0.63 Å
- 1PCF chain A against the predicted model P53999: TM-score 0.95, RMSD 0.69 Å
- 1PCF chain A against the predicted model P53999: TM-score 0.95, RMSD 0.69 Å
- 7E4W chain A against the predicted model P53999: TM-score 0.95, RMSD 0.72 Å
- 7E4W chain A against the predicted model P53999: TM-score 0.95, RMSD 0.72 Å
- 2C62 chain A against the predicted model P53999: TM-score 0.93, RMSD 0.87 Å
- 2C62 chain A against the predicted model P53999: TM-score 0.93, RMSD 0.87 Å
- 2PHE chain A against the predicted model P53999: TM-score 0.84, RMSD 1.40 Å
- 2PHE chain A against the predicted model P53999: TM-score 0.84, RMSD 1.40 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.