AlphaFold monomer V2.0 prediction for mio-dependent tyrosine 2,3-aminomutase (Q8GMG0)

Structure

1 distinct chain · 56% helix, 6% strand (DSSP).

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 2RJS · Sgtam bound to substrate mimic · an experimental structure of the same protein · chain A against B, TM-score 0.98
• 3KDZ · X-ray crystal structure of a tyrosine aminomutase mutant construct with bound ligand · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 3KDY · X-ray crystal structure of tyrosine aminomutase mutant construct · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 2OHY · X-ray crystal structure of tyrosine aminomutase from streptomyces globisporus · an experimental structure of the same protein · chain A against B, TM-score 0.98
• 2RJR · Substrate mimic bound to sgtam · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 2QVE · Crystal structure of sgtam bound to mechanism based inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 2RJS · SgTAM bound to substrate mimic · an experimental structure of the same protein · chain A against B, TM-score 0.97
• 3KDZ · X-ray crystal structure of a tyrosine aminomutase mutant construct with bound ligand · an experimental structure of the same protein · chain A against B, TM-score 0.97
• 3KDY · X-ray crystal structure of tyrosine aminomutase mutant construct · an experimental structure of the same protein · chain A against A, TM-score 0.97

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q8GMG0
• Elsewhere: UniProt Q8GMG0 · AlphaFold DB Q8GMG0