UniProt Q8GMG0
Tyrosine aminomutase (Q8GMG0)
Tyrosine aminomutase (UniProt Q8GMG0), EC 4.3.1.3, 5.4.3.6: 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 114 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8GMG0
- Protein
- Tyrosine aminomutase
- EC
- 4.3.1.3, 5.4.3.6
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 114 · 12 records with a druggable one
Structures
13 records of Q8GMG0 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OHY | X-ray Crystal Structure of Tyrosine Aminomutase from streptomyces globisporus | x-ray diffraction | A, B | — | 9 (best 0.63) |
| 2OHY | X-ray crystal structure of tyrosine aminomutase from streptomyces globisporus | x-ray diffraction | A, B | — | 9 (best 0.55) |
| 2QVE | Crystal Structure of SgTAM bound to mechanism based inhibitor | x-ray diffraction | A, B | 247 | 8 (best 0.62) |
| 2QVE | Crystal structure of sgtam bound to mechanism based inhibitor | x-ray diffraction | A, B | 247 | 8 (best 0.56) |
| 2RJR | Substrate mimic bound to SgTAM | x-ray diffraction | A, B | 295 | 10 (best 0.63) |
| 2RJR | Substrate mimic bound to sgtam | x-ray diffraction | A, B | 295 | 10 (best 0.62) |
| 2RJS | SgTAM bound to substrate mimic | x-ray diffraction | A, B | 296 | 8 (best 0.63) |
| 2RJS | Sgtam bound to substrate mimic | x-ray diffraction | A, B | 296 | 8 (best 0.53) |
| 3KDY | X-ray crystal structure of tyrosine aminomutase mutant construct | x-ray diffraction | A, B | — | 9 (best 0.61) |
| 3KDY | X-ray crystal structure of tyrosine aminomutase mutant construct | x-ray diffraction | A, B | — | 9 (best 0.51) |
| 3KDZ | X-ray crystal structure of a tyrosine aminomutase mutant construct with bound ligand | x-ray diffraction | A, B | TYR | 11 (best 0.63) |
| 3KDZ | X-ray crystal structure of a tyrosine aminomutase mutant construct with bound ligand | x-ray diffraction | A, B | TYR | 11 (best 0.53) |
| Q8GMG0 | AlphaFold monomer V2.0 prediction for mio-dependent tyrosine 2,3-aminomutase (Q8GMG0) | predicted | A | — | 4 (best 0.47) |
Ligands
Experiment against prediction
- 2RJR chain A against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.22 Å
- 2RJR chain A against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.23 Å
- 2QVE chain A against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.23 Å
- 2QVE chain A against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.23 Å
- 2RJS chain A against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.28 Å
- 2RJS chain A against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.28 Å
- 2RJS chain B against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.30 Å
- 2RJS chain B against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.30 Å
- 3KDZ chain B against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.34 Å
- 3KDZ chain B against the predicted model Q8GMG0: TM-score 1.00, RMSD 0.35 Å
Elsewhere
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