MolNFT v1 · #431996 · protein
AlphaFold monomer V2.0 prediction for sorting nexin-27 (Q96L92)
Q96L92: “AlphaFold monomer V2.0 prediction for sorting nexin-27 (Q96L92)”. 9 pockets (best druggability 0.71). MolNFT v1 #431996 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q96L92
- Type
- protein
- Length
- 541 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x299bbf91044DB4548719cdCE91e1900F6B3b185F
- Molecule
- Sorting nexin-27
- UniProt
- Q96L92
- Pockets
- 9 · best druggability 0.71
Structure
1 distinct chain · 30% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-27 | protein | 541 | 30% helix, 26% strand | Q96L92 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 303 | 0.71 | 0.84 | 40 | empty |
| 2 | 344 | 0.56 | 0.75 | 35 | empty |
| 3 | 148 | 0.47 | 0.77 | 32 | empty |
| 4 | 114 | 0.39 | 0.75 | 20 | empty |
| 5 | 82 | 0.35 | 0.75 | 15 | empty |
Compared structures
- 7CT1 · Crystal structure of SNX27 ferm domain in complex with a dlf motif · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 7CT1 · Crystal structure of Snx27 FERM domain in complex with a DLF motif · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 8TTU · Structure of SNX27 FERM complexed with Fam21A repeat 19 (1261 - 1274) · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 8TTT · Structure of SNX27 FERM complexed with Fam21A repeat 15 (1124-1140) · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 7P72 · The PDZ domain of SNX27 complexed with the PDZ-binding motif of MERS-E · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 7P72 · The PDZ domain of SNX27 complexed with the PDZ-binding motif of MERS-E · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 7PCB · The PDZ domain of SNX27 fused with ANXA2 · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 4HAS · Crystal structure of PX domain of human sorting nexin SNX27 · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 4HAS · Crystal structure of px domain of human sorting nexin SNX27 · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 5ZN9 · Crystal structure of px domain · an experimental structure of the same protein · chain A against B, TM-score 0.19
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96L92
- Elsewhere: UniProt Q96L92 · AlphaFold DB Q96L92
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