UniProt Q96L92
Sorting nexin-27 (Q96L92)
Sorting nexin-27 (UniProt Q96L92): 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96L92
- Protein
- Sorting nexin-27
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 21 · 4 records with a druggable one
Structures
12 records of Q96L92 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HAS | Crystal structure of PX domain of human sorting nexin SNX27 | x-ray diffraction | A, B | — | — |
| 4HAS | Crystal structure of px domain of human sorting nexin SNX27 | x-ray diffraction | A, B | — | — |
| 5ZN9 | Crystal structure of px domain | x-ray diffraction | A, B | SO4 | — |
| 6SAK | Structure of the otulincat C129A - SNX27 PDZ domain complex. | x-ray diffraction | C, D | — | — |
| 7CT1 | Crystal structure of SNX27 ferm domain in complex with a dlf motif | x-ray diffraction | A | — | — |
| 7E0B | The crystal structure of sorting nexin 27 and pbm complex | x-ray diffraction | A | — | — |
| 7P72 | The PDZ domain of SNX27 complexed with the PDZ-binding motif of MERS-E | x-ray diffraction | A | CA | 4 (best 0.60) |
| 7P72 | The PDZ domain of SNX27 complexed with the PDZ-binding motif of MERS-E | x-ray diffraction | A | CA | — |
| 7PCB | The PDZ domain of SNX27 fused with ANXA2 | x-ray diffraction | A | CA | — |
| 8TTT | Structure of SNX27 FERM complexed with Fam21A repeat 15 (1124-1140) | x-ray diffraction | A | — | 3 (best 0.69) |
| 8TTU | Structure of SNX27 FERM complexed with Fam21A repeat 19 (1261 - 1274) | x-ray diffraction | A | — | 5 (best 0.74) |
| Q96L92 | AlphaFold monomer V2.0 prediction for sorting nexin-27 (Q96L92) | predicted | A | — | 9 (best 0.71) |
Ligands
Experiment against prediction
- 6SAK chain C against the predicted model Q96L92: TM-score 0.97, RMSD 0.66 Å
- 6SAK chain D against the predicted model Q96L92: TM-score 0.97, RMSD 0.68 Å
- 8TTU chain A against the predicted model Q96L92: TM-score 0.97, RMSD 1.36 Å
- 5ZN9 chain A against the predicted model Q96L92: TM-score 0.97, RMSD 0.78 Å
- 4HAS chain A against the predicted model Q96L92: TM-score 0.96, RMSD 0.83 Å
- 4HAS chain A against the predicted model Q96L92: TM-score 0.96, RMSD 0.83 Å
- 8TTT chain A against the predicted model Q96L92: TM-score 0.96, RMSD 1.38 Å
- 7E0B chain A against the predicted model Q96L92: TM-score 0.96, RMSD 0.82 Å
- 4HAS chain B against the predicted model Q96L92: TM-score 0.96, RMSD 0.87 Å
- 4HAS chain B against the predicted model Q96L92: TM-score 0.96, RMSD 0.87 Å
Elsewhere
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