MolNFT v1 · #428087 · protein
AlphaFold monomer V2.0 prediction for SH3 and multiple ankyrin repeat domains protein 3 (Q9JLU4)
Q9JLU4: “AlphaFold monomer V2.0 prediction for SH3 and multiple ankyrin repeat domains protein 3 (Q9JLU4)”. 9 pockets (best druggability 0.67). MolNFT v1 #428087 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9JLU4
- Type
- protein
- Length
- 1,740 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8A57443634d60193C53f73e465228eE134e3b5e4
- Molecule
- SH3 and multiple ankyrin repeat domains protein 3
- UniProt
- Q9JLU4
- Pockets
- 9 · best druggability 0.67
Structure
1 distinct chain · 14% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH3 and multiple ankyrin repeat domains protein 3 | protein | 1740 | 14% helix, 6% strand | Q9JLU4 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 478 | 0.67 | 0.79 | 56 | empty |
| 2 | 325 | 0.57 | 0.76 | 29 | empty |
| 3 | 209 | 0.49 | 0.75 | 28 | empty |
| 4 | 77 | 0.48 | 0.83 | 23 | empty |
| 5 | 79 | 0.47 | 0.82 | 22 | empty |
Compared structures
- 5G4X · The crystal structure of the SHANK3 N-terminus · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 5G4X · The crystal structure of the SHANK3 N-terminus · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 5OVP · PDZ domain from rat Shank3 bound to the C terminus of CIRL · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 5OVP · PDZ domain from rat SHANK3 bound to the C terminus of cirl · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 5OVC · PDZ domain from rat Shank3 bound to the C terminus of GKAP · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 5OVC · PDZ domain from rat SHANK3 bound to the C terminus of gkap · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 5OVA · Apo PDZ domain from rat SHANK3 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 6EXJ · PDZ domain from rat SHANK3 bound to the C terminus of somatostatin receptor subtype 2 · an experimental structure of the same protein · chain A against C, TM-score 0.05
- 6EXJ · PDZ domain from rat Shank3 bound to the C terminus of somatostatin receptor subtype 2 · an experimental structure of the same protein · chain A against C, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9JLU4
- Elsewhere: UniProt Q9JLU4 · AlphaFold DB Q9JLU4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.