MolNFT v1 · #129815 · protein
PDZ domain from rat SHANK3 bound to the C terminus of cirl
5OVP · SH3 and multiple ankyrin repeat domains protein 3: “PDZ domain from rat SHANK3 bound to the C terminus of cirl”. X-ray diffraction, 1 ligand (ACE). MolNFT v1 #129815 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5OVP
- Type
- protein
- Length
- 102 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SH3 and multiple ankyrin repeat domains protein 3; Adhesion G protein-coupled receptor L1
- UniProt
- Q9JLU4, O88917
- Ligands
- ACE
Structure
x-ray diffraction · 2 distinct chains · 14% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH3 and multiple ankyrin repeat domains protein 3 | protein | 96 | 15% helix, 35% strand | Q9JLU4 |
| B | Adhesion G protein-coupled receptor L1 | protein | 6 | 0% helix, 67% strand | O88917 |
Ligands and binding sites
- ACE · Acetyl group · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 510 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 5OVP · PDZ domain from rat Shank3 bound to the C terminus of CIRL · the same entry in another collection · chain A against A, TM-score 1.00
- Q9JLU4 · AlphaFold monomer V2.0 prediction for SH3 and multiple ankyrin repeat domains protein 3… · a predicted model of the same protein · chain A against A, TM-score 0.97
- O88917 · AlphaFold monomer V2.0 prediction for adhesion G protein-coupled receptor L1 (O88917) · a predicted model of the same protein · chain B against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9JLU4
- Every structure of UniProt O88917
- Elsewhere: RCSB PDB 5OVP · PDBe 5OVP · UniProt Q9JLU4 · UniProt O88917
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