UniProt Q9JLU4
SH3 and multiple ankyrin repeat domains protein 3 (Q9JLU4)
SH3 and multiple ankyrin repeat domains protein 3 (UniProt Q9JLU4): 15 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9JLU4
- Protein
- SH3 and multiple ankyrin repeat domains protein 3
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 1 record with a druggable one
Structures
16 records of Q9JLU4 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2F3N | Crystal Structure of the native Shank SAM domain. | x-ray diffraction | A, B, C | — | — |
| 2F3N | Crystal structure of the native shank SAM domain. | x-ray diffraction | A, B, C | — | — |
| 2F44 | Crystal Structure of the Zinc-bound Shank SAM domain | x-ray diffraction | A, B, C | — | — |
| 2F44 | Crystal structure of the zinc-bound shank SAM domain | x-ray diffraction | A, B, C | — | — |
| 5G4X | The crystal structure of the SHANK3 N-terminus | x-ray diffraction | A | — | — |
| 5G4X | The crystal structure of the SHANK3 N-terminus | x-ray diffraction | A | — | — |
| 5O99 | Unconventional SH3 domain from the postsynaptic density scaffold protein Shank3 | x-ray diffraction | B, A | — | — |
| 5O99 | Unconventional SH3 domain from the postsynaptic density scaffold protein SHANK3 | x-ray diffraction | B, A | — | — |
| 5OVA | Apo PDZ domain from rat SHANK3 | x-ray diffraction | A, B | — | — |
| 5OVC | PDZ domain from rat Shank3 bound to the C terminus of GKAP | x-ray diffraction | A | CL | — |
| 5OVC | PDZ domain from rat SHANK3 bound to the C terminus of gkap | x-ray diffraction | A | ACE, CL | — |
| 5OVP | PDZ domain from rat Shank3 bound to the C terminus of CIRL | x-ray diffraction | A | — | — |
| 5OVP | PDZ domain from rat SHANK3 bound to the C terminus of cirl | x-ray diffraction | A | ACE | — |
| 6EXJ | PDZ domain from rat Shank3 bound to the C terminus of somatostatin receptor subtype 2 | x-ray diffraction | A, C | — | 1 (best 0.48) |
| 6EXJ | PDZ domain from rat SHANK3 bound to the C terminus of somatostatin receptor subtype 2 | x-ray diffraction | A, C | ACE | — |
| Q9JLU4 | AlphaFold monomer V2.0 prediction for SH3 and multiple ankyrin repeat domains protein 3 (Q9JLU4) | predicted | A | — | 9 (best 0.67) |
Ligands
Experiment against prediction
- 2F3N chain C against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.28 Å
- 2F3N chain C against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.28 Å
- 2F3N chain B against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.33 Å
- 2F3N chain B against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.33 Å
- 5G4X chain A against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.86 Å
- 5G4X chain A against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.86 Å
- 2F44 chain C against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.33 Å
- 2F44 chain C against the predicted model Q9JLU4: TM-score 0.99, RMSD 0.33 Å
- 2F3N chain A against the predicted model Q9JLU4: TM-score 0.98, RMSD 0.36 Å
- 2F3N chain A against the predicted model Q9JLU4: TM-score 0.98, RMSD 0.36 Å
Elsewhere
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