MolNFT v1 · #427960 · protein
AlphaFold monomer V2.0 prediction for SH2 domain-containing protein 1A (O60880)
O60880: “AlphaFold monomer V2.0 prediction for SH2 domain-containing protein 1A (O60880)”. 1 pocket (best druggability 0.36). MolNFT v1 #427960 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O60880
- Type
- protein
- Length
- 128 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb32Db384ED6E8dDDA70db1730f5C9f8010365dbB
- Molecule
- SH2 domain-containing protein 1A
- UniProt
- O60880
- Pockets
- 1 · best druggability 0.36
Structure
1 distinct chain · 15% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH2 domain-containing protein 1A | protein | 128 | 15% helix, 25% strand | O60880 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.36 | 0.79 | 17 | empty |
Compared structures
- 1M27 · Crystal structure of SAP/FynSH3/SLAM ternary complex · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 1M27 · Crystal structure of SAP/FYNSH3/SLAM ternary complex · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 1D4T · Crystal structure of the xlp protein sap in complex with a slam peptide · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 1D4T · Crystal structure of the xlp protein sap in complex with a slam peptide · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 1D4W · Crystal structure of the xlp protein sap in complex with slam phosphopeptide · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 1D4W · Crystal structure of the xlp protein sap in complex with slam phosphopeptide · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 1KA6 · SAP/SH2D1A bound to peptide n-pY · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 1KA6 · SAP/SH2D1A bound to peptide N-py · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 1KA7 · SAP/SH2D1A bound to peptide N-Y-C · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 1KA7 · SAP/SH2D1A bound to peptide n-Y-c · an experimental structure of the same protein · chain A against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60880
- Elsewhere: UniProt O60880 · AlphaFold DB O60880
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