UniProt O60880
SH2 domain-containing protein 1A (O60880)
SH2 domain-containing protein 1A (UniProt O60880): 12 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O60880
- Protein
- SH2 domain-containing protein 1A
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
13 records of O60880 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D1Z | Crystal structure of the xlp protein sap | x-ray diffraction | A, B, C, D | — | — |
| 1D1Z | Crystal structure of the xlp protein sap | x-ray diffraction | A, B, C, D | — | — |
| 1D4T | Crystal structure of the xlp protein sap in complex with a slam peptide | x-ray diffraction | A | — | — |
| 1D4T | Crystal structure of the xlp protein sap in complex with a slam peptide | x-ray diffraction | A | — | — |
| 1D4W | Crystal structure of the xlp protein sap in complex with slam phosphopeptide | x-ray diffraction | A, B | — | — |
| 1D4W | Crystal structure of the xlp protein sap in complex with slam phosphopeptide | x-ray diffraction | A, B | — | — |
| 1KA6 | SAP/SH2D1A bound to peptide n-pY | solution nmr | A | — | — |
| 1KA6 | SAP/SH2D1A bound to peptide N-py | solution nmr | A | — | — |
| 1KA7 | SAP/SH2D1A bound to peptide n-Y-c | solution nmr | A | — | — |
| 1KA7 | SAP/SH2D1A bound to peptide N-Y-C | solution nmr | A | — | — |
| 1M27 | Crystal structure of SAP/FynSH3/SLAM ternary complex | x-ray diffraction | A | — | — |
| 1M27 | Crystal structure of SAP/FYNSH3/SLAM ternary complex | x-ray diffraction | A | — | — |
| O60880 | AlphaFold monomer V2.0 prediction for SH2 domain-containing protein 1A (O60880) | predicted | A | — | 1 (best 0.36) |
Experiment against prediction
- 1M27 chain A against the predicted model O60880: TM-score 0.98, RMSD 0.65 Å
- 1M27 chain A against the predicted model O60880: TM-score 0.98, RMSD 0.65 Å
- 1D4W chain B against the predicted model O60880: TM-score 0.98, RMSD 0.56 Å
- 1D4W chain B against the predicted model O60880: TM-score 0.98, RMSD 0.56 Å
- 1D4T chain A against the predicted model O60880: TM-score 0.97, RMSD 0.81 Å
- 1D4T chain A against the predicted model O60880: TM-score 0.97, RMSD 0.81 Å
- 1D4W chain A against the predicted model O60880: TM-score 0.96, RMSD 0.94 Å
- 1D4W chain A against the predicted model O60880: TM-score 0.96, RMSD 0.94 Å
- 1D1Z chain A against the predicted model O60880: TM-score 0.94, RMSD 1.03 Å
- 1D1Z chain A against the predicted model O60880: TM-score 0.94, RMSD 1.03 Å
Elsewhere
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