MolNFT v1 · #427069 · protein
AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 6 (Q9Y3B4)
Q9Y3B4: “AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 6 (Q9Y3B4)”. 3 pockets (best druggability 0.34). MolNFT v1 #427069 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Y3B4
- Type
- protein
- Length
- 125 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9D7B50F95DEcF2b800b00D0aC632219403773eD8
- Molecule
- Splicing factor 3B subunit 6
- UniProt
- Q9Y3B4
- Pockets
- 3 · best druggability 0.34
Structure
1 distinct chain · 36% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Splicing factor 3B subunit 6 | protein | 125 | 36% helix, 20% strand | Q9Y3B4 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 81 | 0.34 | 0.75 | 18 | empty |
| 2 | 72 | 0.34 | 0.76 | 18 | empty |
| 3 | 51 | 0.27 | 0.73 | 10 | empty |
Compared structures
- 3LQV · Branch Recognition by SF3b14 · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 3LQV · Branch recognition by SF3B14 · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 2F9D · 2.5 ångström resolution structure of the spliceosomal protein P14 bound to region of… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 2F9D · 2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of… · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 2F9J · 3.0 angstrom resolution structure of a Y22M mutant of the spliceosomal protein p14 bound… · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 2F9J · 3.0 ångström resolution structure of a Y22M mutant of the spliceosomal protein P14 bound… · an experimental structure of the same protein · chain A against A, TM-score 0.89
- 7Q4O · Substrate-bound a-like U2 snrnp · an experimental structure of the same protein · chain A against F, TM-score 0.71
- 7DVQ · Cryo-EM structure of the activated human minor spliceosome (minor bact complex) · an experimental structure of the same protein · chain A against 5, TM-score 0.66
- 7ABI · Human pre-bact-2 spliceosome · an experimental structure of the same protein · chain A against z, TM-score 0.66
- 5Z58 · Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström. · an experimental structure of the same protein · chain A against 5, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y3B4
- Elsewhere: UniProt Q9Y3B4 · AlphaFold DB Q9Y3B4
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