UniProt Q9Y3B4
Splicing factor 3B subunit 6 (Q9Y3B4)
Splicing factor 3B subunit 6 (UniProt Q9Y3B4): 47 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y3B4
- Protein
- Splicing factor 3B subunit 6
- Experimental structures
- 47
- Predicted models
- 1
- Pockets
- 13 · 9 records with a druggable one
Structures
48 records of Q9Y3B4 in the MolNFT archive: 47 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2F9D | 2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155 | x-ray diffraction | A, B | — | — |
| 2F9D | 2.5 ångström resolution structure of the spliceosomal protein P14 bound to region of SF3B155 | x-ray diffraction | A, B | — | — |
| 2F9J | 3.0 angstrom resolution structure of a Y22M mutant of the spliceosomal protein p14 bound to a… | x-ray diffraction | A, B | — | — |
| 2F9J | 3.0 ångström resolution structure of a Y22M mutant of the spliceosomal protein P14 bound to a… | x-ray diffraction | A, B | — | — |
| 2FHO | NMR solution structure of the human spliceosomal protein complex p14-SF3b155 | solution nmr | B | — | — |
| 2FHO | NMR solution structure of the human spliceosomal protein complex P14- SF3B155 | solution nmr | B | — | — |
| 3LQV | Branch Recognition by SF3b14 | x-ray diffraction | A, B | — | — |
| 3LQV | Branch recognition by SF3B14 | x-ray diffraction | A, B | — | — |
| 5Z56 | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | electron microscopy | 5 | — | — |
| 5Z57 | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | electron microscopy | 5 | — | 1 (best 0.82) |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | electron microscopy | 5 | — | 1 (best 0.82) |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström. | electron microscopy | 5 | — | — |
| 6AH0 | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | electron microscopy | 5 | — | — |
| 6AH0 | The cryo-EM structure of the precusor of human pre-catalytic spliceosome (pre-B complex) | electron microscopy | 5 | — | — |
| 6AHD | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | electron microscopy | 5 | — | — |
| 6FF4 | human Bact spliceosome core structure | electron microscopy | z | — | — |
| 6FF4 | Human bact spliceosome core structure | electron microscopy | z | — | — |
| 6FF7 | human Bact spliceosome core structure | electron microscopy | z, N | — | — |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | z, N | — | — |
| 6Y53 | human 17S U2 snRNP low resolution part | electron microscopy | z | — | 1 (best 0.52) |
| 6Y53 | Human 17S U2 snrnp low resolution part | electron microscopy | z | — | — |
| 6Y5Q | human 17S U2 snRNP | electron microscopy | z | — | — |
| 6Y5Q | Human 17S U2 snrnp | electron microscopy | z | — | — |
| 7ABG | Human pre-Bact-1 spliceosome | electron microscopy | z | — | — |
| 7ABH | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | electron microscopy | z | — | 1 (best 0.71) |
| 7ABH | Human pre-bact-2 spliceosome (SF3B/U2 snrnp portion) | electron microscopy | z | — | — |
| 7ABI | Human pre-Bact-2 spliceosome | electron microscopy | z | — | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | z | — | — |
| 7DVQ | Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | electron microscopy | 5 | — | — |
| 7DVQ | Cryo-EM structure of the activated human minor spliceosome (minor bact complex) | electron microscopy | 5 | — | — |
| 7Q4O | Substrate-bound A-like U2 snRNP | electron microscopy | F | — | 1 (best 0.68) |
| 7Q4O | Substrate-bound a-like U2 snrnp | electron microscopy | F | — | — |
| 8H6E | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | electron microscopy | 2K | — | — |
| 8H6J | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | electron microscopy | 2K | — | — |
| 8H6K | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | electron microscopy | 2K | — | — |
| 8H6L | Cryo-EM structure of human exon-defined spliceosome in the early B state. | electron microscopy | 2K | — | — |
| 8I0P | The cryo-EM structure of human pre-Bact complex | electron microscopy | 6 | — | 1 (best 0.83) |
| 8I0R | The cryo-EM structure of human Bact-I complex | electron microscopy | 6 | — | — |
| 8QO9 | Cryo-EM structure of a human spliceosomal B complex protomer | electron microscopy | B6 | — | — |
| 8QXD | Cryo-EM structure of the cross-exon pre-B complex | electron microscopy | B6 | — | — |
| 8QZS | Cryo-EM structure of the cross-exon B-like complex | electron microscopy | B6 | — | — |
| 8R08 | Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | electron microscopy | B6 | — | 1 (best 0.83) |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | B6 | — | 1 (best 0.83) |
| 8R0A | Cryo-EM structure of the cross-exon pre-B+5'ss complex | electron microscopy | B6 | — | — |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | B6 | — | — |
| 8RM5 | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | electron microscopy | B6 | — | — |
| 8Y7E | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part | electron microscopy | 5 | — | 2 (best 0.78) |
| Q9Y3B4 | AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 6 (Q9Y3B4) | predicted | A | — | 3 (best 0.34) |
Experiment against prediction
- 3LQV chain B against the predicted model Q9Y3B4: TM-score 0.99, RMSD 0.34 Å
- 3LQV chain B against the predicted model Q9Y3B4: TM-score 0.99, RMSD 0.34 Å
- 3LQV chain A against the predicted model Q9Y3B4: TM-score 0.99, RMSD 0.43 Å
- 3LQV chain A against the predicted model Q9Y3B4: TM-score 0.99, RMSD 0.43 Å
- 7Q4O chain F against the predicted model Q9Y3B4: TM-score 0.99, RMSD 0.43 Å
- 7Q4O chain F against the predicted model Q9Y3B4: TM-score 0.99, RMSD 0.43 Å
- 2F9D chain A against the predicted model Q9Y3B4: TM-score 0.98, RMSD 0.53 Å
- 2F9D chain A against the predicted model Q9Y3B4: TM-score 0.98, RMSD 0.53 Å
- 8QO9 chain B6 against the predicted model Q9Y3B4: TM-score 0.98, RMSD 0.48 Å
- 2F9J chain A against the predicted model Q9Y3B4: TM-score 0.97, RMSD 0.66 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.