MolNFT v1 · #423878 · protein
AlphaFold monomer V2.0 prediction for protein translocase subunit seca (P10408)
P10408: “AlphaFold monomer V2.0 prediction for protein translocase subunit seca (P10408)”. 12 pockets (best druggability 0.74). MolNFT v1 #423878 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P10408
- Type
- protein
- Length
- 901 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x790c4c07E1150B077024d27f74aaD7D05C7840c0
- Molecule
- Protein translocase subunit seca
- UniProt
- P10408
- Pockets
- 12 · best druggability 0.74
Structure
1 distinct chain · 58% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein translocase subunit seca | protein | 901 | 58% helix, 12% strand | P10408 |
Pockets
12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 551 | 0.74 | 0.82 | 57 | empty |
| 2 | 512 | 0.63 | 0.76 | 42 | empty |
| 3 | 169 | 0.63 | 0.84 | 26 | empty |
| 4 | 313 | 0.58 | 0.77 | 40 | empty |
| 5 | 341 | 0.55 | 0.74 | 29 | empty |
Compared structures
- 2VDA · Solution structure of the SecA-signal peptide complex · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 2VDA · Solution structure of the seca-signal peptide complex · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 2FSI · Complex SecA:ADP from Escherichia coli · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 2FSI · Complex SECA:ADP from escherichia COLI · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 2FSG · Complex SecA:ATP from Escherichia coli · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 2FSG · Complex SECA:ATP from escherichia COLI · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 2FSF · Escherichia COLI seca, the preprotein translocase dimeric ATPase · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 2FSF · Escherichia coli SecA, the preprotein translocase dimeric ATPase · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 6GOX · SecA · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 6GOX · SECA · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 2FSH · Complex SecA:AMP-PNP from Escherichia coli · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 2FSH · Complex SECA:AMP-pnp from escherichia COLI · an experimental structure of the same protein · chain A against B, TM-score 0.73
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10408
- Elsewhere: UniProt P10408 · AlphaFold DB P10408
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