MolNFT v2 · #151221 · protein

SecA

6GOX · Protein translocase subunit SecA: “SecA”. X-ray diffraction at 3.5, 7 pockets (best druggability 0.79). MolNFT v2 #151221 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6GOX
Type: protein
Length: 777 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.5
Source: Escherichia coli K-12
Molecule: Protein translocase subunit SecA
UniProt: P10408
Pockets: 7 · best druggability 0.79

Structure

x-ray diffraction · resolution 3.5 · 1 distinct chain · 56% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein translocase subunit SecA	protein	777	56% helix, 10% strand	P10408

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	997	0.79	0.81	104	empty
2	151	0.61	0.84	22	empty
3	135	0.48	0.78	24	empty
4	145	0.43	0.75	14	empty
5	66	0.43	0.81	19	empty

Compared structures

6GOX · SECA · the same entry in another collection · chain A against A, TM-score 1.00
P10408 · AlphaFold monomer V2.0 prediction for protein translocase subunit seca (P10408) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10408
Elsewhere: RCSB PDB 6GOX · PDBe 6GOX · UniProt P10408

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