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MolNFT v1 · #423024 · protein

AlphaFold monomer V2.0 prediction for small RNA degrading nuclease 1 (A3KPE8)

A3KPE8: “AlphaFold monomer V2.0 prediction for small RNA degrading nuclease 1 (A3KPE8)”. 4 pockets (best druggability 0.53). MolNFT v1 #423024 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
A3KPE8
Type
protein
Length
409 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
Molecule
Small RNA degrading nuclease 1
UniProt
A3KPE8
Pockets
4 · best druggability 0.53

Structure

1 distinct chain · 41% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASmall RNA degrading nuclease 1protein40941% helix, 21% strandA3KPE8

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12490.530.7620empty
21880.530.7821empty
31900.500.7723empty
4560.310.7617empty

Compared structures

  • 5Z9X · Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate · an experimental structure of the same protein · chain A against A, TM-score 0.69
  • 5Z9X · Arabidopsis small RNA degrading nuclease 1 in complex with an RNA substrate · an experimental structure of the same protein · chain A against A, TM-score 0.69
  • 5Z9Z · The C-terminal rrm domain of arabidopsis small RNA degrading nuclease 1… · an experimental structure of the same protein · chain A against A, TM-score 0.24
  • 5Z9Z · The C-terminal RRM domain of Arabidopsis SMALL RNA DEGRADING NUCLEASE 1… · an experimental structure of the same protein · chain A against A, TM-score 0.24

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