GL1X · GenesisL1 explorer

MolNFT v1 · #421472 · protein

AlphaFold monomer V2.0 prediction for sex comb on midleg-like protein 2 (Q9UQR0)

Q9UQR0: “AlphaFold monomer V2.0 prediction for sex comb on midleg-like protein 2 (Q9UQR0)”. 3 pockets (best druggability 0.72). MolNFT v1 #421472 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9UQR0
Type
protein
Length
700 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x8ed8ad559dA83256eAa95ABFDE527E15c9080462
Molecule
Sex comb on midleg-like protein 2
UniProt
Q9UQR0
Pockets
3 · best druggability 0.72

Structure

1 distinct chain · 18% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASex comb on midleg-like protein 2protein70018% helix, 13% strandQ9UQR0

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111810.720.76111empty
22340.510.7531empty
32060.470.7424empty

Compared structures

  • 2VYT · The mbt repeats of human SCML2 bind to peptides containing mono methylated lysine. · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 2VYT · The MBT repeats of human SCML2 bind to peptides containing mono methylated lysine. · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 2BIV · Crystal structure of the wild-type MBT domains of Human SCML2 · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 2BIV · Crystal structure of the wild-type mbt domains of human SCML2 · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 4EDU · The mbt repeats of human SCML2 in a complex with histone H2A peptide · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 4EDU · The MBT repeats of human SCML2 in a complex with histone H2A peptide · an experimental structure of the same protein · chain A against A, TM-score 0.30
  • 1OI1 · Crystal structure of the mbt domains of human SCML2 · an experimental structure of the same protein · chain A against A, TM-score 0.29
  • 1OI1 · Crystal Structure of the MBT domains of Human SCML2 · an experimental structure of the same protein · chain A against A, TM-score 0.29

Analyse

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