MolNFT v1 · #415637 · protein
AlphaFold monomer V2.0 prediction for disease resistance protein RUN1 (V9M398)
V9M398: “AlphaFold monomer V2.0 prediction for disease resistance protein RUN1 (V9M398)”. 14 pockets (best druggability 0.73). MolNFT v1 #415637 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- V9M398
- Type
- protein
- Length
- 1,331 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
- Molecule
- Disease resistance protein RUN1
- UniProt
- V9M398
- Pockets
- 14 · best druggability 0.73
Structure
1 distinct chain · 30% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Disease resistance protein RUN1 | protein | 1331 | 30% helix, 16% strand | V9M398 |
Pockets
14 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1153 | 0.73 | 0.76 | 92 | empty |
| 2 | 317 | 0.71 | 0.84 | 37 | empty |
| 3 | 320 | 0.65 | 0.81 | 40 | empty |
| 4 | 176 | 0.58 | 0.81 | 22 | empty |
| 5 | 128 | 0.54 | 0.82 | 24 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 7RX1 · Crystal structure of the tir domain from the grapevine disease resistance protein RUN1 · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 7RX1 · Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 7S2Z · Crystal structure of the E100A mutant tir domain from the grapevine disease resistance… · an experimental structure of the same protein · chain A against B, TM-score 0.13
- 7S2Z · Crystal structure of the E100A mutant TIR domain from the grapevine disease resistance… · an experimental structure of the same protein · chain A against B, TM-score 0.13
- 6O0W · Crystal structure of the tir domain from the grapevine disease resistance protein RUN1 in… · an experimental structure of the same protein · chain A against A, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt V9M398
- Elsewhere: UniProt V9M398 · AlphaFold DB V9M398
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