MolNFT v1 · #386884 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q9Z9H6)
Q9Z9H6: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q9Z9H6)”. 3 pockets (best druggability 0.47). MolNFT v1 #386884 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Z9H6
- Type
- protein
- Length
- 315 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- DNA-directed RNA polymerase subunit alpha
- UniProt
- Q9Z9H6
- Pockets
- 3 · best druggability 0.47
Structure
1 distinct chain · 31% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit alpha | protein | 315 | 31% helix, 32% strand | Q9Z9H6 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 104 | 0.47 | 0.80 | 20 | empty |
| 2 | 85 | 0.42 | 0.79 | 14 | empty |
| 3 | 70 | 0.38 | 0.78 | 20 | empty |
Compared structures
- 5TMF · Re-refinement of thermus thermophilus RNA polymerase · an experimental structure of the same protein · chain A against A, TM-score 0.71
- 5TMC · Re-refinement of thermus thermopiles DNA-directed RNA polymerase structure · an experimental structure of the same protein · chain A against A, TM-score 0.71
- 5X22 · Crystal structure of thermus thermophilus transcription initiation complex with gpa and… · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 5D4D · Crystal structure of thermus thermophilus product complex for transcription initiation… · an experimental structure of the same protein · chain A against K, TM-score 0.70
- 5D4C · Crystal structure of thermus thermophilus product complex for transcription initiation… · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 5D4E · Crystal structure of thermus thermophilus product complex for transcription initiation… · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 4Q4Z · Thermus thermophilus RNA polymerase de novo transcription initiation complex · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 4Q4Z · Thermus thermophilus RNA polymerase de novo transcription initiation complex · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 5E18 · T. thermophilus transcription initiation complex having a yyy discriminator sequence and… · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 5E17 · T. thermophilus transcription initiation complex having a rrr discriminator sequence and… · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 5E17 · T. thermophilus transcription initiation complex having a RRR discriminator sequence and… · an experimental structure of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Z9H6
- Elsewhere: UniProt Q9Z9H6 · AlphaFold DB Q9Z9H6
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