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AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q9Z9H6)

Analyse AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9Z9H6
Type
protein
Length
315 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
DNA-directed RNA polymerase subunit alpha
UniProt
Q9Z9H6
Pockets
3 · best druggability 0.47

Structure

1 distinct chain · 31% helix, 32% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-directed RNA polymerase subunit alphaprotein31531% helix, 32% strandQ9Z9H6

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11040.470.8020empty
2850.420.7914empty
3700.380.7820empty

Compared structures

  • 5TMF · Re-refinement of thermus thermophilus RNA polymerase · an experimental structure of the same protein · chain A against A, TM-score 0.71
  • 5TMF · Re-refinement of thermus thermophilus RNA polymerase · an experimental structure of the same protein · chain A against A, TM-score 0.71
  • 5TMC · Re-refinement of thermus thermopiles DNA-directed RNA polymerase structure · an experimental structure of the same protein · chain A against A, TM-score 0.71
  • 5TMC · Re-refinement of Thermus thermopiles DNA-directed RNA polymerase structure · an experimental structure of the same protein · chain A against A, TM-score 0.71
  • 5X22 · Crystal structure of Thermus thermophilus transcription initiation complex with GpA and… · an experimental structure of the same protein · chain A against K, TM-score 0.71
  • 5X22 · Crystal structure of thermus thermophilus transcription initiation complex with gpa and… · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 5D4D · Crystal structure of thermus thermophilus product complex for transcription initiation… · an experimental structure of the same protein · chain A against K, TM-score 0.70
  • 5D4C · Crystal structure of thermus thermophilus product complex for transcription initiation… · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 5D4E · Crystal structure of Thermus thermophilus product complex for transcription initiation… · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 5D4E · Crystal structure of thermus thermophilus product complex for transcription initiation… · an experimental structure of the same protein · chain A against A, TM-score 0.70

Analyse

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