GL1X · GenesisL1 explorer

MolNFT v1 · #372632 · protein

AlphaFold monomer V2.0 prediction for 50S ribosomal protein L5 (P12877)

P12877: “AlphaFold monomer V2.0 prediction for 50S ribosomal protein L5 (P12877)”. 1 pocket (best druggability 0.39). MolNFT v1 #372632 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P12877
Type
protein
Length
179 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
Molecule
50S ribosomal protein L5
UniProt
P12877
Pockets
1 · best druggability 0.39

Structure

1 distinct chain · 42% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A50S ribosomal protein L5protein17942% helix, 21% strandP12877

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11000.390.7621empty

Compared structures

  • 8S1U · YlmH bound to stalled 50S subunits with RqcH and PtRNA · an experimental structure of the same protein · chain A against F, TM-score 0.99
  • 8BUU · ARE-ABCF VmlR2 bound to a 70S ribosome · an experimental structure of the same protein · chain A against F, TM-score 0.97
  • 7OPE · Rqch dr variant bound to 50S-peptidyl-tRNA-rqcp rqc complex (rigid body refinement) · an experimental structure of the same protein · chain A against H, TM-score 0.96
  • 6HA1 · Cryo-EM structure of a 70S Bacillus subtilis ribosome translating the ErmD leader peptide… · an experimental structure of the same protein · chain A against F, TM-score 0.95
  • 6HA8 · Cryo-EM structure of the ABCF protein VmlR bound to the Bacillus subtilis ribosome · an experimental structure of the same protein · chain A against F, TM-score 0.95
  • 6HTQ · Stringent response control by a bifunctional RelA enzyme in the presence and absence of… · an experimental structure of the same protein · chain A against F, TM-score 0.94
  • 5NJT · Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S… · an experimental structure of the same protein · chain A against Z, TM-score 0.93
  • 3J9W · Cryo-EM structure of the Bacillus subtilis MifM-stalled ribosome complex · an experimental structure of the same protein · chain A against BG, TM-score 0.92
  • 6TPQ · RNase M5 bound to 50S ribosome with precursor 5S rRNA · an experimental structure of the same protein · chain A against Z, TM-score 0.90
  • 7AQD · Structure of the bacterial RQC complex (Translocating State) · an experimental structure of the same protein · chain A against F, TM-score 0.90
  • 7AQD · Structure of the bacterial rqc complex (translocating state) · an experimental structure of the same protein · chain A against F, TM-score 0.90
  • 7AQC · Structure of the bacterial rqc complex (decoding state) · an experimental structure of the same protein · chain A against F, TM-score 0.90

Analyse

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