MolNFT v1 · #311157 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 39 (P39682)
P39682: “AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 39 (P39682)”. 5 pockets (best druggability 0.59). MolNFT v1 #311157 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P39682
- Type
- protein
- Length
- 629 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
- Molecule
- Pre-mRNA-processing factor 39
- UniProt
- P39682
- Pockets
- 5 · best druggability 0.59
Structure
1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-processing factor 39 | protein | 629 | 66% helix, 1% strand | P39682 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 165 | 0.59 | 0.82 | 25 | empty |
| 2 | 87 | 0.51 | 0.83 | 20 | empty |
| 3 | 164 | 0.46 | 0.76 | 27 | empty |
| 4 | 84 | 0.43 | 0.79 | 14 | empty |
| 5 | 131 | 0.40 | 0.74 | 19 | empty |
Compared structures
- 5ZWN · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom… · an experimental structure of the same protein · chain A against U, TM-score 0.75
- 5ZWN · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 ångström… · an experimental structure of the same protein · chain A against U, TM-score 0.75
- 6N7X · S. cerevisiae U1 snrnp · an experimental structure of the same protein · chain A against E, TM-score 0.74
- 6N7R · Saccharomyces cerevisiae spliceosomal E complex (ACT1) · an experimental structure of the same protein · chain A against E, TM-score 0.74
- 6N7P · S. cerevisiae spliceosomal E complex (UBC4) · an experimental structure of the same protein · chain A against E, TM-score 0.73
- 7OQE · Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against D, TM-score 0.73
- 7OQC · The U1 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against D, TM-score 0.73
- 6G90 · Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP… · an experimental structure of the same protein · chain A against D, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39682
- Elsewhere: UniProt P39682 · AlphaFold DB P39682
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