MolNFT v1 · #311061 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 17 (P40968)
P40968: “AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 17 (P40968)”. 3 pockets (best druggability 0.79). MolNFT v1 #311061 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40968
- Type
- protein
- Length
- 455 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC96bf460fCE06DE673487c108d3C845a605dCf24
- Molecule
- Pre-mRNA-processing factor 17
- UniProt
- P40968
- Pockets
- 3 · best druggability 0.79
Structure
1 distinct chain · 6% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-processing factor 17 | protein | 455 | 6% helix, 35% strand | P40968 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 837 | 0.79 | 0.82 | 75 | empty |
| 2 | 184 | 0.54 | 0.79 | 26 | empty |
| 3 | 207 | 0.48 | 0.75 | 24 | empty |
Compared structures
- 5YLZ · Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against T, TM-score 0.69
- 5YLZ · Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against T, TM-score 0.69
- 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against M, TM-score 0.65
- 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against o, TM-score 0.64
- 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against o, TM-score 0.64
- 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against o, TM-score 0.61
- 5MPS · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against o, TM-score 0.61
- 5GMK · Cryo-EM structure of the catalytic step I spliceosome (C complex) at 3.4 ångström… · an experimental structure of the same protein · chain A against n, TM-score 0.57
- 6J6Q · Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom · an experimental structure of the same protein · chain A against n, TM-score 0.57
- 6J6Q · Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström · an experimental structure of the same protein · chain A against n, TM-score 0.57
- 6J6N · Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström · an experimental structure of the same protein · chain A against n, TM-score 0.57
- 6J6G · Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström · an experimental structure of the same protein · chain A against n, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40968
- Elsewhere: UniProt P40968 · AlphaFold DB P40968
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