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AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 17 (P40968)

Analyse AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 17 (P40968) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P40968
Type
protein
Length
455 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xC96bf460fCE06DE673487c108d3C845a605dCf24
Molecule
Pre-mRNA-processing factor 17
UniProt
P40968
Pockets
3 · best druggability 0.79

Structure

1 distinct chain · 6% helix, 35% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-mRNA-processing factor 17protein4556% helix, 35% strandP40968

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18370.790.8275empty
21840.540.7926empty
32070.480.7524empty

Compared structures

  • 9DTR · Structure of the yeast post-catalytic P complex spliceosome at 2.3 Angstrom resolution · an experimental structure of the same protein · chain A against o, TM-score 0.71
  • 5YLZ · Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against T, TM-score 0.69
  • 5YLZ · Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against T, TM-score 0.69
  • 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against M, TM-score 0.65
  • 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against M, TM-score 0.65
  • 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against o, TM-score 0.64
  • 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against o, TM-score 0.64
  • 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against o, TM-score 0.61
  • 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against o, TM-score 0.61
  • 5MPS · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against o, TM-score 0.61
  • 5MPS · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against o, TM-score 0.61
  • 5GMK · Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom… · an experimental structure of the same protein · chain A against n, TM-score 0.57

Analyse

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