MolNFT v1 · #311052 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP11 (Q07350)
Q07350: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP11 (Q07350)”. 4 pockets (best druggability 0.54). MolNFT v1 #311052 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q07350
- Type
- protein
- Length
- 266 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5f16694a000281156834B5aF7C1a168819505c33
- Molecule
- Pre-mRNA-splicing factor PRP11
- UniProt
- Q07350
- Pockets
- 4 · best druggability 0.54
Structure
1 distinct chain · 32% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing factor PRP11 | protein | 266 | 32% helix, 21% strand | Q07350 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 267 | 0.54 | 0.76 | 33 | empty |
| 2 | 60 | 0.38 | 0.80 | 15 | empty |
| 3 | 75 | 0.34 | 0.75 | 14 | empty |
| 4 | 60 | 0.33 | 0.76 | 13 | empty |
Compared structures
- 5NRL · Structure of a pre-catalytic spliceosome · an experimental structure of the same protein · chain A against U, TM-score 0.49
- 4DGW · Crystal Structure of the SF3a splicing factor complex of U2 snRNP · an experimental structure of the same protein · chain A against C, TM-score 0.48
- 4DGW · Crystal structure of the SF3A splicing factor complex of U2 snrnp · an experimental structure of the same protein · chain A against C, TM-score 0.48
- 6G90 · Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP… · an experimental structure of the same protein · chain A against U, TM-score 0.45
- 6G90 · Prespliceosome structure provides insight into spliceosome assembly and regulation (map… · an experimental structure of the same protein · chain A against U, TM-score 0.45
- 7OQE · Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) · an experimental structure of the same protein · chain A against U, TM-score 0.41
- 7OQE · Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against U, TM-score 0.41
- 7OQB · The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against U, TM-score 0.41
- 7OQB · The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) · an experimental structure of the same protein · chain A against U, TM-score 0.41
- 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom · an experimental structure of the same protein · chain A against v, TM-score 0.36
- 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström · an experimental structure of the same protein · chain A against v, TM-score 0.36
- 5ZWM · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom… · an experimental structure of the same protein · chain A against v, TM-score 0.36
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07350
- Elsewhere: UniProt Q07350 · AlphaFold DB Q07350
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