UniProt Q07350
Pre-mRNA-splicing factor PRP11 (Q07350)
Pre-mRNA-splicing factor PRP11 (UniProt Q07350): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q07350
- Protein
- Pre-mRNA-splicing factor PRP11
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 2 records with a druggable one
Structures
11 records of Q07350 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DGW | Crystal Structure of the SF3a splicing factor complex of U2 snRNP | x-ray diffraction | C | — | — |
| 4DGW | Crystal structure of the SF3A splicing factor complex of U2 snrnp | x-ray diffraction | C | — | — |
| 5GM6 | Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution | electron microscopy | I | ZN | 3 (best 0.88) |
| 5NRL | Structure of a pre-catalytic spliceosome | electron microscopy | U | ZN | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | electron microscopy | v | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | v | — | — |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | electron microscopy | U | ZN | — |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP A2) | electron microscopy | U | ZN | — |
| 7OQB | The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | U | — | — |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | U | — | — |
| Q07350 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP11 (Q07350) | predicted | A | — | 4 (best 0.54) |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 4DGW chain C against the predicted model Q07350: TM-score 0.86, RMSD 2.28 Å
- 4DGW chain C against the predicted model Q07350: TM-score 0.86, RMSD 2.28 Å
- 5GM6 chain I against the predicted model Q07350: TM-score 0.77, RMSD 2.11 Å
- 5NRL chain U against the predicted model Q07350: TM-score 0.63, RMSD 3.55 Å
- 6G90 chain U against the predicted model Q07350: TM-score 0.60, RMSD 2.79 Å
- 6G90 chain U against the predicted model Q07350: TM-score 0.60, RMSD 2.79 Å
- 7OQE chain U against the predicted model Q07350: TM-score 0.57, RMSD 2.41 Å
- 7OQB chain U against the predicted model Q07350: TM-score 0.57, RMSD 2.41 Å
- 5ZWO chain v against the predicted model Q07350: TM-score 0.53, RMSD 3.17 Å
- 5ZWO chain v against the predicted model Q07350: TM-score 0.53, RMSD 3.17 Å
Elsewhere
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