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MolNFT v1 · #283009 · protein

AlphaFold monomer V2.0 prediction for osteoclast-associated immunoglobulin-like receptor (Q8IYS5)

Q8IYS5: “AlphaFold monomer V2.0 prediction for osteoclast-associated immunoglobulin-like receptor (Q8IYS5)”. 1 pocket (best druggability 0.32). MolNFT v1 #283009 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q8IYS5
Type
protein
Length
282 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x3298b100681D3A2372Bba3b2f282750dD71629B9
Molecule
Osteoclast-associated immunoglobulin-like receptor
UniProt
Q8IYS5
Pockets
1 · best druggability 0.32

Structure

1 distinct chain · 5% helix, 32% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AOsteoclast-associated immunoglobulin-like receptorprotein2825% helix, 32% strandQ8IYS5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1730.320.7415empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 5EIQ · Human oscar ligand-binding domain · an experimental structure of the same protein · chain A against A, TM-score 0.64
  • 5CJB · Human osteoclast associated receptor (oscar) in complex with a collagen-like peptide · an experimental structure of the same protein · chain A against A, TM-score 0.62
  • 5EIV · Crystal structure of complex of osteoclast-associated immunoglobulin- like receptor… · an experimental structure of the same protein · chain A against B, TM-score 0.62
  • 5EIV · Crystal structure of complex of osteoclast-associated immunoglobulin-like receptor… · an experimental structure of the same protein · chain A against B, TM-score 0.62
  • 5CJ8 · Human osteoclast associated receptor (oscar) extracellular domain · an experimental structure of the same protein · chain A against A, TM-score 0.58
  • 5CJ8 · Human Osteoclast Associated Receptor (OSCAR) extracellular domain · an experimental structure of the same protein · chain A against A, TM-score 0.58

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