MolNFT v1 · #117788 · protein

Human oscar ligand-binding domain

5EIQ · Osteoclast-associated immunoglobulin-like receptor: “Human oscar ligand-binding domain”. X-ray diffraction, 1 pocket (best druggability 0.27). MolNFT v1 #117788 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5EIQ
Type: protein
Length: 188 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Osteoclast-associated immunoglobulin-like receptor
UniProt: Q8IYS5
Pockets: 1 · best druggability 0.27

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Osteoclast-associated immunoglobulin-like receptor	protein	188	2% helix, 50% strand	Q8IYS5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.27	0.74	14	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

5EIQ · Human OSCAR ligand-binding domain · the same entry in another collection · chain A against A, TM-score 1.00
Q8IYS5 · AlphaFold monomer V2.0 prediction for osteoclast-associated immunoglobulin-like receptor… · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8IYS5
Elsewhere: RCSB PDB 5EIQ · PDBe 5EIQ · UniProt Q8IYS5

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