UniProt Q8IYS5
Osteoclast-associated immunoglobulin-like receptor (Q8IYS5)
Osteoclast-associated immunoglobulin-like receptor (UniProt Q8IYS5): 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8IYS5
- Protein
- Osteoclast-associated immunoglobulin-like receptor
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 2 · 0 records with a druggable one
Structures
8 records of Q8IYS5 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5CJ8 | Human Osteoclast Associated Receptor (OSCAR) extracellular domain | x-ray diffraction | A | — | — |
| 5CJ8 | Human osteoclast associated receptor (oscar) extracellular domain | x-ray diffraction | A | — | — |
| 5CJB | Human osteoclast associated receptor (oscar) in complex with a collagen-like peptide | x-ray diffraction | A | — | — |
| 5EIQ | Human OSCAR ligand-binding domain | x-ray diffraction | A | — | 1 (best 0.27) |
| 5EIQ | Human oscar ligand-binding domain | x-ray diffraction | A | — | — |
| 5EIV | Crystal structure of complex of osteoclast-associated immunoglobulin-like receptor (OSCAR) and a… | x-ray diffraction | A, B | NAG, SO4, CL, NA | — |
| 5EIV | Crystal structure of complex of osteoclast-associated immunoglobulin- like receptor (oscar) and a… | x-ray diffraction | A, B | — | — |
| Q8IYS5 | AlphaFold monomer V2.0 prediction for osteoclast-associated immunoglobulin-like receptor (Q8IYS5) | predicted | A | — | 1 (best 0.32) |
Ligands
Experiment against prediction
- 5CJB chain A against the predicted model Q8IYS5: TM-score 0.97, RMSD 1.02 Å
- 5EIV chain B against the predicted model Q8IYS5: TM-score 0.95, RMSD 1.34 Å
- 5EIV chain B against the predicted model Q8IYS5: TM-score 0.95, RMSD 1.34 Å
- 5EIV chain A against the predicted model Q8IYS5: TM-score 0.95, RMSD 1.36 Å
- 5EIV chain A against the predicted model Q8IYS5: TM-score 0.95, RMSD 1.36 Å
- 5EIQ chain A against the predicted model Q8IYS5: TM-score 0.94, RMSD 1.33 Å
- 5EIQ chain A against the predicted model Q8IYS5: TM-score 0.94, RMSD 1.33 Å
- 5CJ8 chain A against the predicted model Q8IYS5: TM-score 0.87, RMSD 2.07 Å
- 5CJ8 chain A against the predicted model Q8IYS5: TM-score 0.87, RMSD 2.07 Å
Elsewhere
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