MolNFT v1 · #115427 · protein
Human osteoclast associated receptor (oscar) in complex with a collagen-like peptide
5CJB · Osteoclast-associated immunoglobulin-like receptor: “Human osteoclast associated receptor (oscar) in complex with a collagen-like peptide”. X-ray diffraction, 1 pocket (best druggability 0.35). MolNFT v1 #115427 on GenesisL1: 3D…
- PDB
- 5CJB
- Type
- protein
- Length
- 247 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Osteoclast-associated immunoglobulin-like receptor; Collagen-like peptide
- UniProt
- Q8IYS5
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 3 distinct chains · 1% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Osteoclast-associated immunoglobulin-like receptor | protein | 179 | 2% helix, 51% strand | Q8IYS5 |
| B, D | Collagen-like peptide | protein | 23 | 0% helix, 0% strand | — |
| C | Collagen-like peptide | protein | 22 | 0% helix, 0% strand | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 81 | 0.35 | 0.75 | 19 | empty |
Interfaces
5 interfaces between chains.
- B–D · 692 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 673 Ų buried · 7 hydrogen bonds · protein-protein
- C–D · 632 Ų buried · 6 hydrogen bonds · protein-protein
- A–C · 399 Ų buried · 2 hydrogen bonds · protein-protein
- A–B · 366 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 18 modified, 2 disulfide (hydroxylation, disulfide).
Compared structures
- 5CJB · Human Osteoclast Associated Receptor (OSCAR) in complex with a collagen-like peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q8IYS5 · AlphaFold monomer V2.0 prediction for osteoclast-associated immunoglobulin-like receptor… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IYS5
- Elsewhere: RCSB PDB 5CJB · PDBe 5CJB · UniProt Q8IYS5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.