MolNFT v1 · #271644 · protein
AlphaFold monomer V2.0 prediction for nucleoporin NUP120 (O43044)
O43044: “AlphaFold monomer V2.0 prediction for nucleoporin NUP120 (O43044)”. 17 pockets (best druggability 0.81). MolNFT v1 #271644 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43044
- Type
- protein
- Length
- 1,136 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB0528e6B785661f8478d3407b5BBb95a745eCE95
- Molecule
- Nucleoporin NUP120
- UniProt
- O43044
- Pockets
- 17 · best druggability 0.81
Structure
1 distinct chain · 44% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoporin NUP120 | protein | 1136 | 44% helix, 20% strand | O43044 |
Pockets
17 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1113 | 0.81 | 0.82 | 64 | empty |
| 2 | 546 | 0.77 | 0.84 | 57 | empty |
| 3 | 610 | 0.76 | 0.83 | 48 | empty |
| 4 | 676 | 0.71 | 0.78 | 70 | empty |
| 5 | 610 | 0.70 | 0.79 | 55 | empty |
Compared structures
- 4FHN · Nup37-Nup120 full-length complex from Schizosaccharomyces pombe · an experimental structure of the same protein · chain A against B, TM-score 0.82
- 4FHN · NUP37-NUP120 full-length complex from schizosaccharomyces pombe · an experimental structure of the same protein · chain A against B, TM-score 0.82
- 4FHM · NUP37-NUP120(AA1-961) complex from schizosaccharomyces pombe · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 4FHM · Nup37-Nup120(aa1-961) complex from Schizosaccharomyces pombe · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 4GQ2 · S. pombe Nup120-Nup37 complex · an experimental structure of the same protein · chain A against M, TM-score 0.77
- 4GQ2 · S. pombe NUP120-NUP37 complex · an experimental structure of the same protein · chain A against M, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43044
- Elsewhere: UniProt O43044 · AlphaFold DB O43044
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