MolNFT v1 · #264813 · protein
AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF2 (Q15599)
Q15599: “AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF2 (Q15599)”. 1 pocket (best druggability 0.29). MolNFT v1 #264813 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15599
- Type
- protein
- Length
- 337 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1B3A5eB89516aec5394e2B424e966Cd5dBBe2F8d
- Molecule
- NA(+)/H(+) exchange regulatory cofactor nhe-RF2
- UniProt
- Q15599
- Pockets
- 1 · best druggability 0.29
Structure
1 distinct chain · 20% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NA(+)/H(+) exchange regulatory cofactor nhe-RF2 | protein | 337 | 20% helix, 19% strand | Q15599 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.29 | 0.75 | 14 | empty |
Compared structures
- 2HE4 · The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting… · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 2HE4 · The crystal structure of the second PDZ domain of human nherf-2 (SLC9A3R2) interacting… · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 4P0C · Crystal structure of NHERF2 PDZ1 domain in complex with LPA2 · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 4P0C · Crystal Structure of NHERF2 PDZ1 Domain in Complex with LPA2 · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 2OCS · The crystal structure of the first PDZ domain of human nherf-2 (SLC9A3R2) · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 2OCS · The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 2D11 · Crystal structure of the radixin ferm domain complexed with the nherf-2 C-terminal tail… · an experimental structure of the same protein · chain A against E, TM-score 0.05
- 2D11 · Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail… · an experimental structure of the same protein · chain A against E, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15599
- Elsewhere: UniProt Q15599 · AlphaFold DB Q15599
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