UniProt Q15599
NA(+)/H(+) exchange regulatory cofactor nhe-RF2 (Q15599)
NA(+)/H(+) exchange regulatory cofactor nhe-RF2 (UniProt Q15599): 8 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15599
- Protein
- NA(+)/H(+) exchange regulatory cofactor nhe-RF2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
9 records of Q15599 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2D11 | Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide | x-ray diffraction | E, F, G, H | — | — |
| 2D11 | Crystal structure of the radixin ferm domain complexed with the nherf-2 C-terminal tail peptide | x-ray diffraction | E, F, G, H | — | — |
| 2HE4 | The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode… | x-ray diffraction | A | — | — |
| 2HE4 | The crystal structure of the second PDZ domain of human nherf-2 (SLC9A3R2) interacting with a mode… | x-ray diffraction | A | — | — |
| 2OCS | The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) | x-ray diffraction | A | — | — |
| 2OCS | The crystal structure of the first PDZ domain of human nherf-2 (SLC9A3R2) | x-ray diffraction | A | — | — |
| 4P0C | Crystal Structure of NHERF2 PDZ1 Domain in Complex with LPA2 | x-ray diffraction | A | — | — |
| 4P0C | Crystal structure of NHERF2 PDZ1 domain in complex with LPA2 | x-ray diffraction | A | — | — |
| Q15599 | AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF2 (Q15599) | predicted | A | — | 1 (best 0.29) |
Experiment against prediction
- 2HE4 chain A against the predicted model Q15599: TM-score 0.93, RMSD 1.48 Å
- 2HE4 chain A against the predicted model Q15599: TM-score 0.93, RMSD 1.48 Å
- 2OCS chain A against the predicted model Q15599: TM-score 0.92, RMSD 1.23 Å
- 2OCS chain A against the predicted model Q15599: TM-score 0.92, RMSD 1.23 Å
- 4P0C chain A against the predicted model Q15599: TM-score 0.91, RMSD 1.53 Å
- 4P0C chain A against the predicted model Q15599: TM-score 0.91, RMSD 1.53 Å
- 2D11 chain G against the predicted model Q15599: TM-score 0.61, RMSD 0.91 Å
- 2D11 chain G against the predicted model Q15599: TM-score 0.61, RMSD 0.91 Å
- 2D11 chain E against the predicted model Q15599: TM-score 0.57, RMSD 1.51 Å
- 2D11 chain E against the predicted model Q15599: TM-score 0.57, RMSD 1.51 Å
Elsewhere
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