MolNFT v1 · #262680 · protein
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (Q91WD5)
Q91WD5: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial…”. 1 pocket (best druggability 0.31). MolNFT v1 #262680 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q91WD5
- Type
- protein
- Length
- 463 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
- UniProt
- Q91WD5
- Pockets
- 1 · best druggability 0.31
Structure
1 distinct chain · 45% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | protein | 463 | 45% helix, 11% strand | Q91WD5 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.31 | 0.77 | 12 | empty |
Compared structures
- 8IBD · Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature · an experimental structure of the same protein · chain A against D, TM-score 0.90
- 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against D1, TM-score 0.90
- 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 6ZTQ · Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at… · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2… · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2… · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 6G72 · Mouse mitochondrial complex I in the deactive state · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 7AK6 · Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a · an experimental structure of the same protein · chain A against D, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91WD5
- Elsewhere: UniProt Q91WD5 · AlphaFold DB Q91WD5
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