GL1X · GenesisL1 explorer

MolNFT v1 · #262680 · protein

AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (Q91WD5)

Q91WD5: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial…”. 1 pocket (best druggability 0.31). MolNFT v1 #262680 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q91WD5
Type
protein
Length
463 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
UniProt
Q91WD5
Pockets
1 · best druggability 0.31

Structure

1 distinct chain · 45% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialprotein46345% helix, 11% strandQ91WD5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1500.310.7712empty

Compared structures

  • 8IBD · Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature · an experimental structure of the same protein · chain A against D, TM-score 0.90
  • 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against D1, TM-score 0.90
  • 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 6ZTQ · Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at… · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2… · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2… · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 6G72 · Mouse mitochondrial complex I in the deactive state · an experimental structure of the same protein · chain A against D, TM-score 0.89
  • 7AK6 · Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a · an experimental structure of the same protein · chain A against D, TM-score 0.88

Analyse

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